Distilling GeneChips

نویسندگان

  • Soo Ling Lim
  • Peter J. Bentley
  • William B. Langdon
چکیده

EDITORIAL Editorial I was not able to attend GECCO this year, but everybody told me it was as great as usual and I am sure that all the people who attended it enjoyed it a lot! I had not spent the second week of July in Milan since 2000, when I could not attend GECCO-2000 in Las Vegas. Thus, spending the GECCO week at work while all my friends were enjoying themselves in Philly, has been kind of weird. Indeed, I already checked the flights to Amsterdam and I plan to book a ticket soon. So I guess I will see you at GECCO-2013! Today, we start a brand new SIGEVOlution volume with a very nice cover and two even nicer articles. One, presents AppEco an artificial life framework that has been applied to the modelling of a very well-known ecosystem, the Apple's App Store. If you want to become a successful developer for any mobile market, you should definitively read this article. AppEco appeared in the April issue of the New Scientist (check the article here). The article published here is a reprint of the paper presented at GECCO-2012 in July, with the permission of ACM. The next paper by William B. Langdon describes an application of genetic programming to the long-term outcome prediction of breast cancer using Emerald, a supercomputer containing 1008 x86 CPU cores and 372 nVidia M2090 Tesla GPUs. That's massive parallel EC! The cover shows a graph from a study regarding the effect of app publicity using AppEco that Soo Ling and Peter recently published in ALife XIII. Consider it an appetizer of what you might want to read after you are done with the papers in this issue. the board members, Dave Davis and Martin Pelikan, and to the friends who help me in this adventure. App developers are constantly competing against each other to win more downloads for their apps. With hundreds of thousands of apps in these online stores, what strategy should a developer use to be successful? Should they innovate, make many similar apps, optimise their own apps or just copy the apps of others? Looking more deeply, how does a complex app ecosystem perform when developers choose to use different strategies? This paper investigates these questions using AppEco, the first Artificial Life model of mobile application ecosystems. In AppEco, developer agents build and upload apps to the app store; user …

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Smallpox virus resequencing GeneChips can also rapidly ascertain species status for some zoonotic non-variola orthopoxviruses.

We recently developed a set of seven resequencing GeneChips for the rapid sequencing of Variola virus strains in the WHO Repository of the Centers for Disease Control and Prevention. In this study, we attempted to hybridize these GeneChips with some known non-Variola orthopoxvirus isolates, including monkeypox, cowpox, and vaccinia viruses, for rapid detection.

متن کامل

An overview of image-processing methods for Affymetrix GeneChips

We present an overview of image-processing methods for Affymetrix GeneChips. All GeneChips are affected to some extent by spatially coherent defects and image processing has a number of potential impacts on the downstream analysis of GeneChip data. Fortunately, there are now a number of robust and accurate algorithms, which identify the most disabling defects. One group of algorithms concentrat...

متن کامل

Systematic order-dependent effect in expression values, variance, detection calls and differential expression in Affymetrix GeneChips®

MOTIVATION Affymetrix GeneChips are common 3' profiling platforms for quantifying gene expression. Using publicly available datasets of expression profiles from human and mouse experiments, we sought to characterize features of GeneChip data to better compare and evaluate analyses for differential expression, regulation and clustering. We uncovered an unexpected order dependence in expression d...

متن کامل

The use of Affymetrix GeneChips as a tool for studying alternative forms of RNA.

We are developing a computational pipeline to use surveys of Affymetrix GeneChips as a discovery tool for unravelling some of the biology associated with post-transcriptional processing of RNA. This work involves the integration of a number of bioinformatics resources, from comparing annotations to processing images to determining the structure of transcripts. The rapidly growing datasets of Ge...

متن کامل

Distilling dialogues - A method using natural dialogue corpora for dialogue systems development

We report on a method for utilising corpora collected in natural settings. It is based on distilling (re-writing) natural dialogues to elicit the type of dialogue that would occur if one the dialogue participants was a computer instead of a human. The method is a complement to other means such asWizard of Oz-studies and un-distilled natural dialogues. We present the distilling method and guidel...

متن کامل

Comparison of non-human primate and human whole blood tissue gene expression profiles.

Gene expression profiling is an important tool in the development of medical countermeasures against chemical warfare agents (CWAs). Non-human primates (NHPs), specifically the rhesus macaque (Macaca mulatta), the cynomologus macaque (Macaca fascicularis), and the African green monkey (Chlorocebus aethiops), are vital models in the development of CWA prophylactics, therapeutics, and diagnostics...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2012